Free Ebook Introducing Epigenetics: A Graphic Guide
Free Ebook Introducing Epigenetics: A Graphic Guide
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Introducing Epigenetics: A Graphic Guide
Free Ebook Introducing Epigenetics: A Graphic Guide
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About the Author
Cath Ennis has a research background in genetics, genomics and cancer, and works as a grant writer and project manager in Vancouver, Canada. She writes about epigenetics and other topics for The Guardian, has co-written a textbook on stem cell science, and can be found online at enniscath.com.Oliver Pugh is a designer and illustrator.
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Product details
Series: Introducing
Paperback: 176 pages
Publisher: Icon Books (April 11, 2017)
Language: English
ISBN-10: 9781848318625
ISBN-13: 978-1848318625
ASIN: 1848318626
Product Dimensions:
4.8 x 0.8 x 6.5 inches
Shipping Weight: 5 ounces (View shipping rates and policies)
Average Customer Review:
4.0 out of 5 stars
26 customer reviews
Amazon Best Sellers Rank:
#228,193 in Books (See Top 100 in Books)
As the book explains, while DNA is the code that defines an organism, epigenetics provides the notes on how to translate the code into a real live organism.The book is formatted for modern readers. It is short as Kindle books go – only 1385 locations. It is divided into chapters about one page each in length. I include the chapter index at the end of the review. It is rich in diagrams.In writing such a book, the author must strike a balance between readability and completeness. She has to make some assumptions about the reader. This book appears to assume that the reader will be college educated, not flummoxed by the introduction of new technical terms, and somewhat familiar with genetics. In other words, it is not for everybody.I am 50 years out of college but have read much of the popular literature on genetics, starting with Dawkins' Selfish Gene. I found that the book demanded my attention, forcing me to reread a few chapters in order to fully grasp the concepts, but in the end quite satisfying.DNA, the blueprint for our bodies, is invariant. Every cell of the body contains the same long, complex DNA molecules. However, DNA always exists among other, supporting molecules, which do differ from cell to cell. These epigenetic assistants control how the information from the DNA is translated into building proteins for the various types of cells within the body.DNA stands for diribonucleic acid – the double helix, half from the father, half from the mother. RNA stands for ribonucleic acid, the more general form. Proteins are formed by what is called messenger RNA. These molecules are copied from short subsets of the whole DNA molecule. Messenger RNA tells the cell how to build the proteins required to be, for instance, a brain cell or a liver cell.The structures surrounding DNA in a given cell includes markers that control which part of the DNA will be used as templates for building amino acids within the cell and which will be ignored. There are different structures for different cells.As the chapter titles below indicate, a lot of things affect the epigenetic material surrounding DNA. Among these are aging and exposure to chemicals such as those in tobacco. While the DNA may not change within an individual, the body parts made according to that DNA model do change via epigenetics.Epigenetic diagnoses for disease, and epigenetic-based cures for disease our already in place, and many more appear to be on the horizon. This book will be useful reading for investors interested in the next big things in biotechnology. It will help them read investment product prospectuses and annual reports from companies involved in esoteric new technologies.The book is truly a five-star effort. The author deserves a great deal of credit for striking such a good balance among readability, completeness and bulk.The chapter titles:Genes, RNA and ProteinsChromosomes, Nucleosomes and ChromatinDNA Replication and MitosisMeiosis and InheritanceBeyond the DNA Sequence: Gene RegulationNature and NurtureTwin StudiesThe History of EpigeneticsThe Modern Understanding of Epigenetic ModificationsDNA MethylationHistone ModificationsChromatin RemodellingNuclear LocationRNAInteractions Between Different Epigenetic ModificationsEpigenetics Explains What Genetics Alone CannotEpigenetic Changes During Embryonic DevelopmentX Chromosome InactivationHow Our Environment Affects Our GenesNot So Identical TwinsEpigenetic InheritanceEpigenetic Inheritance in Animal ModelsHuman Epigenetic Inheritance: The Dutch Hunger WinterHuman Epigenetic Inheritance: ÖverkalixMechanisms of Epigenetic InheritanceEpigenetics in EvolutionEpigenetics in Disease: AgeingEpigenetics in Disease: Inherited Mutations in EpigeneticRegulatorsEpigenetics in Disease: Imprinting ErrorsThe Epigenetics of CancerEpigenetics in MedicineStem Cell TherapiesEpigenetics and PseudoscienceThe Future of EpigeneticsEpigenomicsNew Epigenetic ModificationsThe EpitranscriptomeEpigenetic EditingEpigen-EthicsLooking AheadGlossaryRecommended Further ReadingAuthor’s Acknowledgements
I bought this book for a friend who is interested in science and was asking me some questions about epigenetic. I looked through several books here at Amazon and decided to by this particular book. I was interested in the graphical approach to introducing the subject as I have a couple of other books on DNA sequencing and protein synthesis that presented the material in a nice way with great graphics. Unfortunately I was un impressed with the book and felt that the title was misleading. Although there were lots of pictures I didn't feel that they added much to the presentation of the material. Still I do think that it does provide an introduction to the subject for nonscientists.
While it is a good introduction to an interesting aspect of genetics, I felt that the illustrations, which were supposed to helpful, instead were at time distracting from the main narrative. I also do think that this would NOT be good for somebody with NO basic genetic knowledge. Overall, it's interesting for those who have a basic knowledge of biology and genetics, but would not recommend as an introductory book for someone with no background.
I was hoping the addition of visuals would contribute to the reader's understanding of the content, but the graphics are merely slightly entertaining commentary and do not at all aid in explaining the concepts of the book. Too bad. It's an ok book but not sure I would recommend.
Great and easy to comprehend introduction to a complex subject. Would recommend to anyone that are interested to learn more about genetics and epigenetics in particular.
Interesting information presented in an easy to understand format. Definitely part of the future of medicine.
This is a fascinating but very complicated topic that has a great deal of importance in the future of life as we know it. This book went a long way toward helping clarify certain things and doing it with humor. It helped in my class papers.
Good briefly demonstration for someone who has experience in DNA and genetics but not for everyone.
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